• Paediatric anaesthesia · Mar 2001

    Randomized Controlled Trial Comparative Study Clinical Trial

    A comparison of the respiratory effects of high concentrations of halothane and sevoflurane.

    • R Walpole, J Olday, M Haetzman, G B Drummond, and E Doyle.
    • Department of Anaesthesia, Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK.
    • Paediatr Anaesth. 2001 Mar 1;11(2):157-60.

    AbstractWe studied the respiratory effects of the administration of either 5% halothane or 8% sevoflurane in 70% nitrous oxide (N2O) for 5 min in 21 boys aged 1-5 years. A similar degree of ventilatory depression was noted with both agents. Minute volume fell by approximately 50% as a result of a reduction in tidal volume despite an increase in respiratory rate.

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