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Comparative Study
Value of chest radiography in a tuberculosis prevention programme for HIV-infected people, Botswana.
- B Mosimaneotsile, E A Talbot, T L Moeti, N M Hone, G Moalosi, H J Moffat, E J Lee, and T A Kenyon.
- BOTUSA Project, US Centers for Disease Control and Prevention, Gaborone, Botswana. baru1@cdc.gov
- Lancet. 2003 Nov 8;362(9395):1551-2.
AbstractTo exclude tuberculosis, WHO/UNAIDS recommends considering medical history, symptom screen, and chest radiograph before starting tuberculosis prevention in people infected with HIV. The value of a chest radiograph for this purpose is unknown. We prospectively assessed 935 HIV-infected outpatients seeking isoniazid preventive therapy. Of 935 patients, 692 (74%) had no signs or symptoms of tuberculosis. Of these 692, 123 (18%) were lost during the chest radiograph process, and one (0.2%) of the remaining 563 was diagnosed with tuberculosis on the basis of the chest radiograph. A screening chest radiograph should not be required routinely for asymptomatic people taking isoniazid as preventive treatment in settings able to screen for signs and symptoms of tuberculosis.
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