• Kidney international · Oct 2015

    Comment

    Does early-start renal replacement therapy improve outcomes for patients with acute kidney injury?

    • John R Prowle and Andrew Davenport.
    • Adult Critical Care Unit, Royal London Hospital, Barts Health NHS Trust, London, UK.
    • Kidney Int. 2015 Oct 1; 88 (4): 670-3.

    AbstractThere is a paucity of high-quality evidence to guide clinicians on thresholds for commencement of renal replacement therapy (RRT) in critically ill patients with acute kidney injury (AKI), and wide international practice variation. Wald et al. report a pilot randomized trial examining accelerated use of RRT for moderate AKI in the intensive care unit, providing a workable design for a definitive trial examining the timing of RRT in critical illness.

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