• Chest · Nov 2016

    Review

    Management of myositis related interstitial lung disease.

    • Julie Morisset, Cheilonda Johnson, Eric Rich, Harold R Collard, and Joyce S Lee.
    • Department of Medicine, University of California San Francisco, San Francisco, CA.
    • Chest. 2016 Nov 1; 150 (5): 1118-1128.

    AbstractInterstitial lung disease (ILD) is a frequent pulmonary manifestation and an important cause of morbidity and mortality in patients with idiopathic inflammatory myopathy. Myositis-related ILD presents a therapeutic challenge for clinicians, as there are no available guidelines to help with management decisions. This review covers the existing evidence on the pharmacologic and nonpharmacologic management of myositis-related ILD, highlighting the lack of randomized controlled data to guide treatment. Given the absence of existing guidelines to inform treatment decisions, we provide a comprehensive summary, including dosing, side effects, and suggested monitoring of the commonly used immunosuppressive agents and a proposed treatment algorithm based on the existing literature.Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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