• T Rakza, A Fily, S Mur, T Pennaforte, and L Storme.
• Pôle Femme-Mère-Nouveau-Né, hôpital Jeanne-de-Flandre, CHRU de Lille, 2, rue Eugène-Aviné, 59037 Lille cedex 1, France; EA 4489, environnement périnatal et santé, faculté de médecine, université Lille II, 42, rue Paul-Duez, 59800 Lille, France. Electronic address: thameur.rakza@chru-lille.fr.
• Ann Fr Anesth Reanim. 2014 Nov 1;33(11):572-5.

ObjectiveThe flow rate of intravenous administration of vasoactive agents should be steady in order to prevent changes in hemodynamics. In the newborns, because the flow rate is often lower than 1mL/h, it is difficult to switch of the syringe. The aim of our study was to compare the variations of concentration of active substance delivered after a manual or an automatic switch off the syringe with three different volumes (10mL, 20mL and 50mL).Materials And MethodsGlucose solution (10g/L) was used to simulate the administered substance. Saline was administered in "Y" simultaneously with the glucose solution through a catheter. The infused substance was collected at the tip of the catheter. The glucose concentration was measured at 15min-interval for 3hours.ResultsThe manual switch of the syringe was associated with a significant alteration of the flow rate, lasting more than 15min. In contrast, the automatic switch of syringes was associated with no change of the flow rate, especially with small-volume syringes (10mL).ConclusionIn newborns, in order to prevent the change in flow rate of drugs after a switch of syringes, our results suggest the use of syringe-pump with built-in automatic switch and small-volume syringes.Copyright © 2014 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier SAS. All rights reserved.

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