• Pediatric dermatology · Nov 2013

    Case Reports

    Successful combination treatment of a patient with progressive juvenile localized scleroderma (morphea) using imatinib, corticosteroids, and methotrexate.

    • Yasuji Inamo and Toyoko Ochiai.
    • Department of General Pediatrics, Nihon University Nerima-Hikarigaoka Hospital, Nihon University School of Medicine, Tokyo, Japan.
    • Pediatr Dermatol. 2013 Nov 1; 30 (6): e191-3.

    AbstractWe report a case of progressive juvenile localized scleroderma (JLS or morphea) treated with a combination of imatinib, corticosteroids, and methotrexate. This therapy halted the progressive skin thickening and the hand and finger joint deformity in the early stages of the disease. We conclude that imatinib used in addition to standard treatment with systemic corticosteroids and methotrexate may be of therapeutic benefit for individuals with JLS.© 2012 Wiley Periodicals, Inc.

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