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Clinics in liver disease · May 2011
Liver transplantation for hepatocellular carcinoma: expanding frontiers and building bridges.
- Howard C Masuoka and Charles B Rosen.
- Division of Gastroenterology and Hepatology, William J. von Liebig Transplant Center, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
- Clin Liver Dis. 2011 May 1; 15 (2): 385-93, vii-x.
AbstractDespite significant advances in nonsurgical treatments of hepatocellular carcinoma, these approaches rarely result in cure. Surgery remains the mainstay of curative therapy for hepatocellular carcinoma. Liver transplantation, in particular, has emerged as one of the most beneficial therapeutic modalities. Questions remain, however, regarding hepatocellular carcinoma surveillance, the choice of surgical resection versus transplantation, the role of chemotherapy, optimal selection criteria for transplantation, and the role of ablative therapies to halt tumor progression and downsize tumors exceeding transplant criteria.Copyright © 2011 Elsevier Inc. All rights reserved.
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