• Am. J. Cardiol. · Mar 2011

    Case Reports

    Carcinoid heart disease without the carcinoid syndrome but with quadrivalvular regurgitation and unsuccessful operative intervention.

    • William Clifford Roberts, Cyril Abie Varughese, Jong Mi Ko, Paul A Grayburn, Robert Frederick Hebeler, and Elizabeth C Burton.
    • Department of Pathology, Baylor University Medical Center, Dallas, TX, USA. wc.roberts@baylorhealth.edu
    • Am. J. Cardiol. 2011 Mar 1; 107 (5): 788-92.

    AbstractA 53-year-old woman is described who underwent mitral and aortic valve replacement and tricuspid valve annuloplasty for pure regurgitation at all 3 valve sites for unrecognized carcinoid heart disease without the carcinoid syndrome 22 days before death. Metastatic carcinoid was not recognized until necropsy, which disclosed a probable ovarian primary but with large hepatic metastases and left-sided cardiac involvement either greater than or equal to the right-sided involvement. Pulmonary hypertension, very unusual in carcinoid heart disease, persisted postoperatively and probably played a role in the patient's early death. Hepatic metastasis with ovarian primary is most unusual in this circumstance.Copyright © 2011 Elsevier Inc. All rights reserved.

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