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Prog. Neuropsychopharmacol. Biol. Psychiatry · Apr 1996
Randomized Controlled Trial Clinical TrialEffect of gabapentin (Neurontin) [corrected] on mood and well-being in patients with epilepsy.
- K R Dimond, A C Pande, L Lamoreaux, and M W Pierce.
- CNS Clinical Research and Development, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, MI, USA.
- Prog. Neuropsychopharmacol. Biol. Psychiatry. 1996 Apr 1; 20 (3): 407-17.
Abstract1. Global improvement data from five double-blind clinical trials of gabapentin as add-on therapy in patients with epilepsy were reviewed to assess the effects of gabapentin on mood. 2. One hundred and ninety-four (46%) of 423 gabapentin-treated patients reported improvements in general well-being as compared with 79 (29%) of the 271 placebo-treated patients. 3. Findings support anecdotal reports of improved affective status among patients taking gabapentin and suggest that the study of gabapentin in psychiatric populations may be warranted.
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