• Burns · Aug 1990

    Debridement of experimental full-thickness skin burns of rats with enzyme fractions derived from pineapple stem.

    • A D Rowan, C W Christopher, S F Kelley, D J Buttle, and H P Ehrlich.
    • Biochemistry Department, Strangeways Research Laboratory, Cambridge, UK.
    • Burns. 1990 Aug 1; 16 (4): 243-6.

    AbstractA limited in vivo study using 12 rats with full-thickness skin burns injuries was carried out. The animals were treated 24 h postburn with two newly discovered enzyme fractions derived from the stem of the pineapple (Ananas comosus). The results indicated that even debridement of the injury could be effected rapidly (within 4 h). Although the details of enzyme formulation and clinical application have yet to be established, these findings clearly suggest that two enzyme fractions from pineapple stem have potential as non-surgical debriding agents.

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