• Tao Xu, Lulong Bo, Jiafeng Wang, Zhenzhen Zhao, Zhiyun Xu, Xiaoming Deng, and Wenzhong Zhu.
• Department of Anesthesiology and Intensive Care Medicine, Changhai hospital, Second Military Medical University, Shanghai, China. zhuwenzh@gmail.com.
• J Cardiothorac Surg. 2013 Jan 1; 8: 204.

BackgroundThe present study was performed to investigate the incidence of early postoperative cognitive dysfunction (POCD) after non-coronary bypass surgery and the potential risk factors in Chinese population.MethodsWe performed a prospective study in a teaching tertiary hospital from May 2012 to August 2012. One hundred and seventy-six adult patients undergoing non-coronary bypass surgery were recruited. Mini-Mental State Examination (MMSE) score was evaluated before and 3 to 5 days after surgery. Patients with a MMSE score reduction of 2 was diagnosed with POCD.ResultsThe general incidence of POCD was 33.0%, with no significant difference between the types of surgeries. In the univariate analysis, POCD associated factors included age, duration of surgery, anesthesia, cardiopulmonary bypass (CPB), cross-clamp and rewarming, and sevoflurane concentration. However, only age, cross-clamp duration and sevoflurane concentration were demonstrated to be independent risk factors for POCD.ConclusionIncidence of early POCD after non-coronary bypass surgery was relatively high in Chinese population. Advanced age, longer aortic cross-clamp duration and lower sevoflurane concentration was associated with a higher incidence of POCD.

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