• Hunan Yi Ke Da Xue Xue Bao · Oct 2001

    [Associated sedation of propofol and midazolam in small dosage and gastroscopy].

    • W L Tang, S J Liu, and X W Jiang.
    • Gastroscope Room, Third Xiangya Hospital, Central South University, Changsha 410013, China.
    • Hunan Yi Ke Da Xue Xue Bao. 2001 Oct 28; 26 (5): 463-5.

    ObjectiveTo search for a sedative method that is more suitable for gastroscopy.MethodsAll of patients were randomly divided into control group and experimental group. The experimental group was treated with propofol and midazolam, the control group was treated with propofol alone. The cumulation dosage of propofol, sedative effect, variation of BP and SaO2 were observed in all patient.ResultsThe cumulative dosage of propofol in the experimental group was lower than that in the control group [(73.21 +/- 18.67) mg and (117.23 +/- 21.57) mg respectively]; the oblivious degree in the experimental group was higher than that in the control group (95.65% and 80.00%); the onset time and the descendant range of BP and SaO2 were also lower in the experimental than those in the control group. There was not remarkable difference in sedative effect and veriviscont time between the control group and the experimental group.ConclusionsIn such a rapid operation of gastroscopy, the dosage of propofol in the experimental group is obviously less than that in the control group, while it does not affect the effect of sedation, the diagnose and cure time in gastroscopy room, and has more security and less cost.

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