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- Thomas M Todoran and Piotr Sobieszczyk.
- Cardiovascular Division, Vascular Medicine Section, Brigham and Women's Hospital, Boston, MA 02115, USA.
- Prog Cardiovasc Dis. 2010 Mar 1; 52 (5): 429-37.
AbstractMassive pulmonary embolism carries a high mortality rate as a result of right ventricular failure. In addition to anticoagulation, systemic thrombolysis is the standard first line of therapy for patients with life-threatening massive pulmonary embolism. Surgical embolectomy is often considered in patients with contraindications to receiving systemic thrombolysis or when thrombolysis has failed. Surgical embolectomy is not without inherent risk and limitations.Although there is a paucity of large clinical trials, available data suggests catheter-based treatment of massive pulmonary embolism restores hemodynamic stability and thus is an alternative to surgical therapy.Copyright 2010 Elsevier Inc. All rights reserved.
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