• Alexander Y Razumovsky, Lavern D Gugino, and Jeffrey H Owen.
• Sentient Medical Systems, Inc., 10151 York Road, Suite 120, Cockeysville, MD 21030, USA. arazumov@surgicalmonitoring.net
• Curr Cardiol Rep. 2006 Feb 1; 8 (1): 17-22.

AbstractCardiac surgery (CS) with cardiopulmonary bypass (CPB) is currently the most common surgery in the United States. Understanding, avoiding, and preventing postoperative complications, including neurologic deficits following CS, represents a great public and economic benefit for society, especially considering our aging population. There is a critical need to identify new strategies that will prevent harmful events during and after CS. At present, experience with neurophysiologic techniques includes the ability to measure cerebral blood flow velocity/emboli and regional cerebral venous oxygen saturation by transcranial Doppler ultrasound, and by near-infrared spectroscopy, respectively. Continuous monitoring of these variables along with systemic hemodynamics will provide a better understanding of mechanisms of brain and other organ injury during CPB. Neuroprotective interventions based on multimodality neurologic monitoring would ideally eliminate postoperative complications and improve patient outcomes.

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