• Can J Anaesth · May 2015

    Case Reports

    [Acute coronary syndrome following a 100 µg carbetocin injection during an emergency Cesarean delivery.]

    • Pierre Jacquenod, Mathilde Cattenoz, Guillaume Canu, Elodie Bois, and Thomas Lieutaud.
    • Service d'anesthésie, Centre hospitalier Fleyriat, Bourg en Bresse, France.
    • Can J Anaesth. 2015 May 1;62(5):513-7.

    PurposePostpartum hemorrhage affects 5% of parturients. Its prevention relies mainly on the administration of oxytocin derivatives. Carbetocin is a newly available analogue of oxytocin but has a considerable incidence of side effects.Clinical FeaturesWe report the case of a woman with no cardiovascular risk factors experiencing an acute coronary syndrome with significant electrocardiogram changes perioperatively after a single injection of carbetocin during an emergency Cesarean delivery. Postoperative cardiac enzyme levels and transthoracic echocardiogram results were normal.ConclusionA 2012 retrospective analysis of the use of carbetocin in our institution revealed an incidence rate for coronary events of 1/245 (0.34%), a rate similar to the ones reported in previous studies. We discuss the management of patients with angina during a Cesarean delivery as well as the plans to care for these patients in the future.

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    This article appears in the collection: Carbetocin at Cesarean Section.

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