• Nature · Oct 1978

    A two-step fibrinogen--fibrin transition in blood coagulation.

    • B Blombäck, B Hessel, D Hogg, and L Therkildsen.
    • Nature. 1978 Oct 12; 275 (5680): 501-5.

    AbstractThe kinetics of the thrombin-catalysed release of fibrino-peptides A and B from human fibrinogen have been investigated and a mechanism correlating the release of fibrinopeptides to fibrin formation is presented. The sequential release of fibrinopeptides results in sequential activation of two sets of polymerisation sites.

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