• J. Int. Med. Res. · Jun 2014

    A study of noninvasive positive-pressure mechanical ventilation in the treatment of acute lung injury with a complex critical care ventilator.

    • Jing Zhang, Jie Cao, Jing Feng, Qi Wu, and Bao-Yuan Chen.
    • Department of Respiratory Diseases, General Hospital of Tianjin Medical University, Tianjin, China.
    • J. Int. Med. Res. 2014 Jun 1; 42 (3): 788-98.

    ObjectiveTo test the hypothesis that there would be better clinical outcomes following the treatment of patients with acute lung injury (ALI) using noninvasive positive-pressure mechanical ventilation (NIPPV) delivered via a complex critical care ventilator compared with a conventional mini-ventilator.MethodsPatients with ALI who required NIPPV were prospectively enrolled and randomly divided between three intervention groups: group A was ventilated using a mini-ventilator; groups B and C were ventilated using a complex critical care ventilator using different settings. Clinical parameters were recorded before and after 8 h of mechanical ventilation.ResultsA total of 51 patients with ALI were enrolled in the study. Clinical parameters in groups B and C underwent greater improvements than those in group A. Group C demonstrated the lowest treatment failure rate (23.5%). Failure rates were highest in group A (58.8%).ConclusionThe findings of this present study suggest that there were more satisfactory clinical outcomes following the treatment of patients with ALI when NIPPV was delivered using a complex critical care ventilator compared with a conventional mini-ventilator.© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

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