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Review Meta Analysis
A Meta-Analysis of the Reliability of the History in Suspected Poisoning.
- Robert Camilleri.
- Mater Dei Hospital, Msida, Malta.
- J Emerg Med. 2015 Jun 1;48(6):679-84.
BackgroundManagement of acute poisoning depends on the reliability of history of the poisoning event.ObjectiveThe objective of this study was to perform a meta-analysis from published data to determine summary measures of reliability of history in suspected acute poisoning.MethodRelevant studies were selected from a search on the Medline database to perform a meta-analysis to calculate pooled estimates of κ statistic for agreement between history of poisoning and laboratory diagnosis.ResultsA total of seven articles were included in the meta-analysis. The κ statistic varied from 0.35 (95% confidence interval [CI] 0.135-0.558) for 3,4-methylenedioxy-N-methylamphetamine (MDMA, also known as ecstasy) to 0.69 (95% CI 0.648-0.733) for paracetamol.ConclusionsA history of paracetamol ingestion is moderately reliable, and further evaluation is required to make a clinical diagnosis of acute poisoning with street drugs.Copyright © 2015 Elsevier Inc. All rights reserved.
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