• Clin J Pain · Sep 1994

    Case Reports

    Successful treatment of postherpetic neuralgia with oral ketamine.

    • V Hoffmann, H Coppejans, M Vercauteren, and H Adriaensen.
    • Department of Anesthesia, University Hospital of Antwerpen, Edegem, Belgium.
    • Clin J Pain. 1994 Sep 1; 10 (3): 240-2.

    ObjectiveTo demonstrate the possibilities of the use of oral ketamine in the treatment of postherpetic neuralgia.SettingA pain clinic in a university hospital.PatientA patient with postherpetic neuralgia of the ophthalmic nerve.InterventionSubcutaneous and later oral ketamine after classical treatment had failed.ResultsA complete recovery was accomplished without any sign of side effects.ConclusionsOral ketamine may provide an alternative in the treatment of postherpetic neuralgia. The possible mechanism of action by its N-methyl-D-aspartate (NMDA) blocking properties is discussed.

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