-
Zhong Nan Da Xue Xue Bao Yi Xue Ban · Feb 2007
[Measurement of activated clotting time during cardiopulmonary bypass in infective endocarditis patients].
- Ling Jiang and Jie-Feng Yu.
- Department of Cardiothoracic Suergery, Second Xiangya Hospital, Central South University, Changsha 410011, China. zxb960@sohu.com
- Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2007 Feb 1; 32 (1): 167-9.
ObjectiveTo investigate the proper dosage of heparin and protamin in treating the patients with infective endocarditis (IE) during the operation.MethodsActivated clotting time (ACT) was measured during and after cardiopulmonary bypass (CPB) in 30 patients with IE and 30 patients with rheumatic heart disease (RHD) respectively.ResultsThe dosage of heparin before bypass in IE group was significantly higher than that of RHD group (P<0.05); the dosage of protamin for neutralization after bypass in IE group was significantly higher than that of RHD group (P<0.05); the ratio of protamin and heparin were 0.76 +/-0.23 in IE group and 0.74 +/-0.12 in RHD group (P>0.05).ConclusionThe dosage of protamin should be increased to 3 mg/kg as the heparin is over 400 U/kg before CPB in the patient with IE, but the ratio of protamin and heparin will not be obviously changed.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..