• Clinics in liver disease · Nov 2011

    Review

    Management of renal dysfunction in patients receiving a liver transplant.

    • Christine Lau, Paul Martin, and Suphamai Bunnapradist.
    • Kidney and Pancreas Transplant Program, Division of Nephrology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA.
    • Clin Liver Dis. 2011 Nov 1; 15 (4): 807-20.

    AbstractRenal dysfunction is a frequent complication in patients with endstage liver disease awaiting orthotopic liver transplantation. Although the stereotypical form of renal dysfunction is the hepatorenal syndrome, common causes of acute kidney injury include prerenal azotemia and acute tubular necrosis in this population. Management involves hemodynamic support, renal replacement therapy, and mitigation of risk factors. Renal dysfunction in a cirrhotic patient usually implies a poor prognosis in the absence of liver transplantation. An important issue is the frequent need for kidney, in addition to liver, transplantation if renal insufficiency has been persistent in a decompensated cirrhotic.Copyright © 2011 Elsevier Inc. All rights reserved.

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