• Rev Chir Orthop Reparatrice Appar Mot · Oct 2004

    [Total hip arthroplasty for the treatment of septic hip arthritis in adults with sickle-cell disease].

    • P Hernigou, T Odent, O Manicom, A Nogier, D Bachir, and F Galacteros.
    • Service de Chirurgie Orthopédique, Hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil Cedex.
    • Rev Chir Orthop Reparatrice Appar Mot. 2004 Oct 1; 90 (6): 557-60.

    Purpose Of The StudySeptic hip arthritis is a recognized complication of sickle-cell disease. The incidence is difficult to assess but is significant since certain authors estimate that 11% of children with sickle-cell disease develop orthopedic complications. We report our experience with hip joint infection in adults with sickle-cell disease.Material And MethodsWe diagnosed ten cases of hip joint infection in seven adults with sickle-cell disease. The characteristic feature of the septic arthritis was the development of a septic focus in a zone of osteonecrosis of the femoral head. Diagnosis was difficult due to the presence of prior hip disease and also the circumstances of development: other infectious foci, septicemia, distant osteomyelitis. The diagnosis was confirmed by joint puncture and isolation of the causal germ. Despite adapted antibiotics and immobilization with traction-suspension, hip joint destruction could not be prevented and all patients became bedridden. Surgery was therefore undertaken to remove the head and neck and institute local antibiotic treatment. A total hip prosthesis was implanted in all patients.ResultsAt 2 to 12 years follow-up, all seven patients had nearly normal hip function (all 10 hips). Recurrent infection nevertheless developed in 2 hips, demonstrating the limitations of this technique.

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