• Rev Assoc Med Bras · Mar 2010

    Multicenter Study Comparative Study

    [Impact of a program for venous thromboembolism prophylaxis in hospitalized patients in four hospitals in Salvador].

    • Ana Thereza C Rocha, Edison Ferreira de Paiva, Danilo Miranda de Araújo, Dulceane Natyara Cardoso, Aline Cristina da Hora Pereira, Antônio Alberto Lopes, and Eduardo S Darzé.
    • Hospital Universitário Professor Edgard Santos, Salvador, BA.
    • Rev Assoc Med Bras. 2010 Mar 1; 56 (2): 197-203.

    UnlabelledThere is a discrepancy between guideline recommendations and practice of venous thromboembolism (VTE) prophylaxis in hospitals worldwide.ObjectiveTo implement a program using a risk-assessment tool (RAT) for VTE and educational lectures based on the Brazilian Guidelines for VTE Prophylaxis for Medical Patients and to evaluate the impact of these tools on adequacy of VTE prophylaxis in 4 hospitals in Salvador, Bahia.MethodsWe performed two cross-sectional surveys before and after the implementation of the program to compare the proportion of patients at-risk of VTE and the changes in the adequacy of VTE prophylaxis.ResultsWe compared the data of 219 medical patients before with 292 patients after the program. The rates of patients with at least one risk factor for VTE and with contraindications (CI) for heparins were similar: 95% vs. 98% (p=0.13), and 42% vs. 34% (p=0.08), respectively. In both studies, 75% vs. 82% (p=0.06) were candidates for prophylaxis, and 44% vs. 55% (p =0.02) were candidates for prophylaxis and had no CI for heparin. After the program there was an increase in the use of mechanical prophylaxis 0.9% vs. 4.5% (p=0.03) and a decrease in pharmacological prophylaxis, 55.3% vs. 47.9% (p=0.04). However, there was a significant increase of use of the recommended doses of heparins, 53% vs. 75 (p<0.001).ConclusionThere is underutilization of VTE prophylaxis in Brazilian hospitals. Strategies based on passive distribution of RAT and educational lectures were not sufficient to improve the practice of prophylaxis, but improved the adequacy of VTE prophylaxis in hospitalized patients.

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