• J Neurosurg Pediatr · Nov 2014

    Review Practice Guideline

    Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 10: Change in ventricle size as a measurement of effective treatment of hydrocephalus.

    • Dimitrios C Nikas, Alexander F Post, Asim F Choudhri, Catherine A Mazzola, Laura Mitchell, Ann Marie Flannery, and Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force.
    • Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois
    • J Neurosurg Pediatr. 2014 Nov 1; 14 Suppl 1: 77-81.

    ObjectThe objective of this systematic review is to answer the following question: Does ventricle size after treatment have a predictive value in determining the effectiveness of surgical intervention in pediatric hydrocephalus?MethodsThe US National Library of Medicine PubMed/MEDLINE database and the Cochrane Database of Systematic Reviews were searched using MeSH headings and key words relevant to change in ventricle size after surgical intervention for hydrocephalus in children. An evidentiary table was assembled summarizing the studies and the quality of evidence (Classes I-III).ResultsSix articles satisfied inclusion criteria for the evidentiary tables for this part of the guidelines. All were Class III retrospective studies. CONCLUSIONS/RECOMMENDATIon: There is insufficient evidence to recommend a specific change in ventricle size as a measurement of the effective treatment of hydrocephalus and as a measurement of the timing and effectiveness of treatments including ventriculoperitoneal shunts and third ventriculostomies.Strength Of RecommendationLevel III, unclear clinical certainty.

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