-
Randomized Controlled Trial
Transfusion strategy for acute upper gastrointestinal bleeding.
- James Handel and Eddy Lang.
- Division of Emergency Medicine,University of Calgary,Calgary,AB.
- Can J Emerg Med. 2015 Sep 1; 17 (5): 582-5.
AbstractClinical question Does a hemoglobin transfusion threshold of 70 g/L yield better patient outcomes than a threshold of 90 g/L in patients with acute upper gastrointestinal bleeding? Article chosen Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368(1):11-21. Study objectives The authors of this study measured mortality, from any cause, within the first 45 days, in patients with acute upper gastrointestinal bleeding, who were managed with a hemoglobin threshold for red cell transfusion of either 70 g/L or 90 g/L. The secondary outcome measures included rate of further bleeding and rate of adverse events.
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