• Obstet. Gynecol. Clin. North Am. · Jun 2014

    Review

    Neonatal opioid withdrawal syndrome.

    • Mary Beth Sutter, Lawrence Leeman, and Andrew Hsi.
    • Department of Family and Community Medicine, University of New Mexico, 2400 Tucker North East, MSC09 5040, Albuquerque, NM 87131, USA. Electronic address: lleeman@salud.unm.edu.
    • Obstet. Gynecol. Clin. North Am. 2014 Jun 1; 41 (2): 317-34.

    AbstractNeonatal opioid withdrawal syndrome is common due to the current opioid addiction epidemic. Infants born to women covertly abusing prescription opioids may not be identified as at risk until withdrawal signs present. Buprenorphine is a newer treatment for maternal opioid addiction and appears to result in a milder withdrawal syndrome than methadone. Initial treatment is with nonpharmacological measures including decreasing stimuli, however pharmacological treatment is commonly required. Opioid monotherapy is preferred, with phenobarbital or clonidine uncommonly needed as adjunctive therapy. Rooming-in and breastfeeding may decease the severity of withdrawal. Limited evidence is available regarding long-term effects of perinatal opioid exposure.Copyright © 2014 Elsevier Inc. All rights reserved.

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