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- J Herzog, M Pinsker, M Wasner, F Steigerwald, S Wailke, G Deuschl, and J Volkmann.
- Department of Neurology, Neurozentrum, Christian-Albrechts-Universität Kiel, Kiel, Germany.
- Mov. Disord. 2007 Apr 15; 22 (5): 679-84.
AbstractRarely, the postoperative management of patients with subthalamic deep brain stimulation (STN-DBS) is complicated by pharmacologically intractable dyskinesias. Here we report that in three of these patients additional stimulation of a proximal contact located within the subthalamic white matter may lead to a significant reduction of dyskinesias associated with STN-DBS. We propose that pallidofugal fiber tracts play a major role in the etiopathology of dyskinesias and their blockade through DBS may explain our observations.
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