• Gerard C C Lim, Emran N Aina, Soon K Cheah, Fuad Ismail, Gwo F Ho, Lye M Tho, Cheng H Yip, Nur A Taib, Kwang J Chong, Jayendran Dharmaratnam, Matin M Abdullah, Ahmad K Mohamed, Kean F Ho, Kananathan Ratnavelu, Chiao M Lim, Kin W Leong, Ibrahim A Wahid, Teck O Lim, and HPMRS Breast Cancer Study Group.
• ClinResearch SB, Kuala Lumpur, Malaysia. limteckonn@gmail.com.
• Bmc Cancer. 2014 Jan 1; 14: 212.

BackgroundCancer is the leading cause of deaths in the world. A widening disparity in cancer burden has emerged between high income and low-middle income countries. Closing this cancer divide is an ethical imperative but there is a dearth of data on cancer services from developing countries.MethodsThis was a multi-center, retrospective observational cohort study which enrolled women with breast cancer (BC) attending 8 participating cancer centers in Malaysia in 2011. All patients were followed up for 12 months from diagnosis to determine their access to therapies. We assess care performance using measures developed by Quality Oncology Practice Initiative, American Society of Clinical Oncology/National Comprehensive Cancer Network, American College of Surgeons' National Accreditation Program for Breast Centers as well as our local guideline.ResultsSeven hundred and fifty seven patients were included in the study; they represent about 20% of incident BC in Malaysia. Performance results were mixed. Late presentation was 40%. Access to diagnostic and breast surgery services were timely; the interval from presentation to tissue diagnosis was short (median = 9 days), and all who needed surgery could receive it with only a short wait (median = 11 days). Performance of radiation, chemo and hormonal therapy services showed that about 75 to 80% of patients could access these treatments timely, and those who could not were because they sought alternative treatment or they refused treatment. Access to Trastuzumab was limited to only 19% of eligible patients.ConclusionsThese performance results are probably acceptable for a middle income country though far below the 95% or higher adherence rates routinely reported by centres in developed countries. High cost trastuzumab was inaccessible to this population without public funding support.

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