• Pediatric emergency care · Apr 2017

    Case Reports

    Pericarditis as the Presenting Feature of Graves Disease in a Pediatric Patient.

    • Danielle Cullen, Neil Munjal, Hannah Chalal, Sriram Ramgopal, Emir Tas, and Selma Witchel.
    • From the *Department of Pediatrics and †Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA.
    • Pediatr Emerg Care. 2017 Apr 1; 33 (4): 268-270.

    AbstractPericarditis is a rare presentation of thyrotoxicosis associated with Graves disease. This association has not been previously described in the pediatric literature. We report a 17-year-old male patient who presented with chest pain, dyspnea, and tachycardia. He was found to have diffuse ST-segment elevation consistent with pericarditis. At presentation, he was noted to have bilateral proptosis. Abnormal thyroid function studies and an elevated thyroid-stimulating hormone receptor antibody level confirmed the diagnosis of Graves thyrotoxicosis. The patient was treated with anti-inflammatory and antithyroid agents and improved in time. We discuss previously reported cases of Graves disease-associated pericarditis in adults, potential etiologies, and management strategies.

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