• Biomarkers · Sep 2012

    Advanced oxidation protein products as prognostic biomarkers for recovery from acute kidney injury after coronary artery bypass grafting.

    • Xinling Liang, Yuanhan Chen, Jian Zhuang, Min Zhang, Weiping Xiong, Huiming Guo, Fen Jiang, Penghua Hu, Dan Guo, and Wei Shi.
    • Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, China.
    • Biomarkers. 2012 Sep 1; 17 (6): 507-12.

    AbstractRecovery from acute kidney injury (AKI) is related to long-term prognosis. This study, involving 56 patients with AKI and 56 controls from a prospective cohort undergoing coronary artery bypass grafting (CABG), investigated the prognostic performance of serum levels of advanced oxidation protein products (AOPPs) for predicting non-recovered AKI and non-completely recovered AKI. AOPP levels increased significantly 7 days after surgery in patients with non-recovered or non-completely recovered AKI. Increased AOPP levels were associated with both types of poor recovery from AKI. Results from receiver-operating characteristic (ROC) curves demonstrated that AOPP levels had good prognostic value for predicting non-recovered and non-completely recovered AKI.

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