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Int J Obstet Anesth · Aug 2016
Case ReportsAnesthetic management of a parturient with Stiff person syndrome for urgent cesarean delivery.
- B T Boettcher, M Muravyea, C Kuo, C Drexler, and P S Pagel.
- Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: bboettcher@mcw.edu.
- Int J Obstet Anesth. 2016 Aug 1; 27: 85-8.
AbstractStiff person syndrome is a rare neurologic disorder with an estimated incidence of 1:1000000. The underlying pathophysiology is truncal and proximal limb muscle stiffness resulting from continuous co-contracture of agonist and antagonist muscle groups concomitant with superimposed episodic muscle spasms. Loss of gamma-aminobutyric acid-mediated inhibition creates chronic excitation manifested by tonic agonist-antagonist muscle contraction. To date, only three case reports referred indirectly to the anesthetic management of parturients with Stiff person syndrome. The authors describe their management of a parturient with Stiff person syndrome who underwent urgent cesarean delivery under epidural anesthesia. Copyright © 2016 Elsevier Ltd. All rights reserved.
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