• Immunity · Oct 2015

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    Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse.

    • Sarah E Church and Jérôme Galon.
    • INSERM, UMRS1138, Laboratory of Integrative Cancer Immunology, Paris, 75006, France; Université Paris Descartes, Paris 75006, France; Cordeliers Research Centre, Université Pierre et Marie Curie Paris 6, Paris 75006, France.
    • Immunity. 2015 Oct 20; 43 (4): 631-3.

    AbstractPredicting cancer patients' response to therapy is essential for curing disease and improving quality of life. Garraway and colleagues demonstrate that the frequency and number of neoantigens, non-synonymous mutations, and adaptive immune genes, but not the assessment of individual recurrent neoantigens or mutations, predicts patient responses to immunotherapy.Copyright © 2015 Elsevier Inc. All rights reserved.

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