• Orthopedics · Oct 2003

    Comparative Study

    A cost analysis of bone morphogenetic protein versus autogenous iliac crest bone graft in single-level anterior lumbar fusion.

    • David W Polly, Stacey J Ackerman, Christopher I Shaffrey, James W Ogilvie, Jeffrey C Wang, Susan W Stralka, Michael S Mafilios, Stephen E Heim, and Harvinder S Sandhu.
    • Orthopedic Surgery Service, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA.
    • Orthopedics. 2003 Oct 1; 26 (10): 1027-37.

    AbstractAn economic model was developed to compare costs of stand-alone anterior lumbar interbody fusion with recombinant human bone morphogenetic protein 2 on an absorbable collagen sponge versus autogenous iliac crest bone graft in a tapered cylindrical cage or a threaded cortical bone dowel. The economic model was developed from clinical trial data, peer-reviewed literature, and clinical expert opinion. The upfront price of bone morphogenetic protein (3380 dollars) is likely to be offset to a significant extent by reductions in the use of other medical resources, particularly if costs incurred during the 2 year period following the index hospitalization are taken into account.

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