• J. Thorac. Cardiovasc. Surg. · Mar 2017

    Impact of cardiac arrest resuscitated donors on heart transplant recipients' outcome.

    • Antonella Galeone, Shaida Varnous, Guillaume Lebreton, Eleodoro Barreda, Sara Hariri, Alain Pavie, and Pascal Leprince.
    • Department of Thoracic and Cardiovascular Surgery, University Pierre et Marie Curie, Paris 6, Assistance Publique des Hôpitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Paris, France. Electronic address: a.galeone@email.it.
    • J. Thorac. Cardiovasc. Surg. 2017 Mar 1; 153 (3): 622-630.

    ObjectiveTo evaluate the influence of cardiac arrest-resuscitated donors (CARDs) on the outcome of heart recipients.MethodsPatients transplanted between July 2004 and December 2012 were divided into 2 groups according to the history of cardiac arrest in donors and their clinical records were retrospectively reviewed.ResultsA total of 584 heart transplantations were performed during the study period, and 117 recipients received an organ from a CARD. There were no differences between the 2 groups with regards to recipient age, sex, cardiomyopathy, preoperative extracorporeal membrane oxygenation, national high emergency waiting list, and redo surgery. Donors who sustained a cardiac arrest were significantly younger (44 [32-51] vs 49 [41-56] years; P < .001), their main cause of death was anoxia (57% vs 1%; P < .001), and they had significantly greater troponin T peak levels (0.51 [0.128-3.108] vs 0.11 [0.04-0.43] ng/mL; P < .001). Median cardiac arrest duration was 15 minutes (5-25). No difference was noted in donors with regards to left ventricular ejection fraction at time of organ procurement (62% ± 8% vs 63% ± 8%; P = .2). There were no differences between the 2 groups with regards to ischemic time (179 ± 60 vs 183 ± 59 minutes; P = .43), need for postoperative extracorporeal membrane oxygenation for primary graft failure (31% vs 30%; P = .993) and 30-days mortality. Recipients receiving an organ from a CARD had a significantly better 10 year survival (69.4% vs 50.4%; P = .017).ConclusionsHistory of cardiac arrest in donors with a preserved left ventricular ejection fraction at time of organ procurement doesn't affect outcome of heart recipients.Copyright © 2016 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

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