• Am. J. Respir. Crit. Care Med. · Mar 2017

    Review

    Fifty Years of Research in ARDS. Is Acute Respiratory Distress Syndrome a Preventable Disease?

    • Hemang Yadav, B Taylor Thompson, and Ognjen Gajic.
    • 1 Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota; and.
    • Am. J. Respir. Crit. Care Med. 2017 Mar 15; 195 (6): 725-736.

    AbstractDespite significant advances in our understanding and management of patients with acute respiratory distress syndrome (ARDS), the morbidity and mortality from ARDS remains high. Given the limited number of effective treatments for established ARDS, the strategic focus of ARDS research has shifted toward identifying patients with or at high risk of ARDS early in the course of the underlying illness, when strategies to reduce the development and progression of ARDS and associated organ failures can be systematically evaluated. In this review, we summarize the rationale, current evidence, and future directions in ARDS prevention.

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