• Chun-Chieh Chiu, Tai-Yuan Chuang, Kwang-Hwa Chang, Chien-Hua Wu, Po-Wei Lin, and Wen-Yen Hsu.
• Department of Physical Medicine and Rehabilitation, Wan Fang Hospital, Taipei Medical University, Taiwan.
• Clin Rehabil. 2015 Feb 1; 29 (2): 184-95.

ObjectiveTo determine the probability of spontaneous disc regression among each type of lumbar herniated disc, using a systematic review.Data SourcesMedline, Cochrane Library, CINAHL, and Web of Science were searched using key words for relevant original articles published before March 2014. Articles were limited to those published in English and human studies.Review MethodsArticles had to: (1) include patients with lumbar disc herniation treated conservatively; (2) have at least two imaging evaluations of the lumbar spine; and (3) exclude patients with prior lumbar surgery, spinal infections, tumors, spondylolisthesis, or spinal stenosis. Two reviewers independently extracted study details and findings. Thirty-one studies met the inclusion criteria. Furthermore, if the classification of herniation matched the recommended classification of the combined Task Forces, the data were used for combined analysis of the probability of disc regression of each type. Nine studies were applicable for probability calculation.ResultsThe rate of spontaneous regression was found to be 96% for disc sequestration, 70% for disc extrusion, 41% for disc protrusion, and 13% for disc bulging. The rate of complete resolution of disc herniation was 43% for sequestrated discs and 15% for extruded discs.ConclusionsSpontaneous regression of herniated disc tissue can occur, and can completely resolve after conservative treatment. Patients with disc extrusion and sequestration had a significantly higher possibility of having spontaneous regression than did those with bulging or protruding discs. Disc sequestration had a significantly higher rate of complete regression than did disc extrusion.© The Author(s) 2014.

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