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- Susan M Smith, John Smucny, and Tom Fahey.
- HRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland Medical School, Dublin.
- JAMA. 2014 Dec 24;312(24):2678-9.
Clinical QuestionAre antibiotics associated with improved outcomes in patients with acute bronchitis?Bottom LinePrescribing antibiotics for acute bronchitis was associated with reduced overall and nighttime cough and with an approximately half-day reduction in duration of cough, in days feeling ill, and in days with impaired activities. However, at follow-up, there were no significant differences in patients receiving antibiotics compared with those receiving placebo in overall clinical improvements or limitations in work or other activities. There was a significant increase in adverse effects in the antibiotic group, particularly gastrointestinal symptoms.
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