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- Julie Brown and Cynthia Farquhar.
- Liggins Institute, University of Auckland, New Zealand.
- JAMA. 2015 Jan 20;313(3):296-7.
Clinical QuestionWhat treatments are associated with improved outcomes for women with endometriosis?Bottom LineThe levonorgestrel-releasing intrauterine system (LNG-IUD), gonadotropin-releasing hormone analogues (GnRHa; nafarelin, leuprolide, buserelin, goserelin, triptorelin), laparoscopic ablation, and excision are associated with relief of pain due to endometriosis. Gonadotropin-releasing hormone analogues and laparoscopic ablation or excision are associated with increased clinical pregnancy rates in women with endometriosis. Gonadotropin-releasing hormone analogues, danazol, and depot progestagens are associated with a higher incidence of adverse events.
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