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The lancet oncology · Feb 2014
ReviewHealth-related quality of life in small-cell lung cancer: a systematic review on reporting of methods and clinical issues in randomised controlled trials.
- Efstathios Zikos, Irina Ghislain, Corneel Coens, Divine E Ediebah, Elizabeth Sloan, Chantal Quinten, Michael Koller, Jan P van Meerbeeck, Hans-Henning Flechtner, Roger Stupp, Athanasios Pallis, Agnes Czimbalmos, Mirjam A G Sprangers, and Andrew Bottomley.
- Quality of Life Department, EORTC Headquarters, Brussels, Belgium. Electronic address: efstathios.zikos@eortc.be.
- Lancet Oncol. 2014 Feb 1; 15 (2): e78-89.
AbstractSmall-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials. Copyright © 2014 Elsevier Ltd. All rights reserved.
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