• Laura A Payne, Laura C Seidman, Kirsten C Lung, Lonnie K Zeltzer, and Jennie C I Tsao.
• Pediatric Pain Program, David Geffen School of Medicine, University of California, 10833 Le Conte Ave., 22-464 MDCC, Los Angeles, CA 90095-1752, USA. LPayne@mednet.ucla.edu
• Pain. 2013 Jan 1; 154 (1): 103-9.

AbstractBoth neuroticism, a higher-order, stable personality trait, and anxiety sensitivity (AS), a lower-order pain-related construct, have been associated with pain, although no research exists examining the relationship of both these constructs to acute pain in children. In the current study, 99 healthy children (53 girls) completed self-report measures of neuroticism and AS before undergoing pain tasks involving cold and pressure pain. We hypothesized that both neuroticism and AS would be correlated with acute pain responses, but that AS would at least partially mediate the relationship between neuroticism and pain responses. Results indicated significant correlations between neuroticism, AS, and anticipatory anxiety, pain intensity and pain bother. Mediational models revealed that AS partially mediated relationships between neuroticism and pain intensity/bother, and fully mediated relationships between neuroticism and anticipatory anxiety. These data suggest that, at least in children, neuroticism may be best understood as a vulnerability factor for elevated pain responses, especially when coupled with a fear of bodily sensations.Copyright © 2012 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

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