-
- Frank LoVecchio, Kenneth Katz, David Watts, and Ian Wood.
- Banner Good Samaritan Regional Poison Center, Maricopa Medical Center, Department of Emergency Medicine, Phoenix, AZ, USA. Frank.LoVecchio@bannerhealth.com
- J Med Toxicol. 2008 Sep 1; 4 (3): 149-50.
IntroductionUnintentional methotrexate (MTX) acute oral overdose is rarely reported.MethodsWe conducted a retrospective chart review of all human exposure calls (>150,000 charts) for MTX ingestions reported to our Poison Center during 2000-2003.ResultsThirteen patients met the criteria. The average amount of MTX ingested was 13.03 mg (data from 7 cases), and the average patient age was 43 years (20 months to 80 years). No significant toxicities occurred.DiscussionAlthough intravenous MTX toxicity can be severe, this does not appear to be a phenomenon associated with either acute unintentional or suicidal oral ingestion.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..