• A & A case reports · Sep 2017

    Case Reports

    Multiple Anesthetic Drug Sensitization in a Hairdresser With Previous Immediate-Type Hypersensitivity to Penicillin: A Case Report.

    • Cristina Petrişor, Nadia Gherman, Manuela Sfichi, Marius Mureşan, and Natalia Hagău.
    • From the Departments of *Anesthesia and Intensive Care and †Allergology and Immunology, University of Medicine and Pharmacy "Iuliu Hatieganu," Cluj-Napoca, Romania; and ‡Department of Immunopathology, Clinical Emergency County Hospital of Cluj, Cluj-Napoca, Romania.
    • A A Case Rep. 2017 Sep 1; 9 (5): 151-153.

    AbstractRisk factors for intraoperative immediate-type hypersensitivity reactions may require allergological evaluation. We report the case of a hairdresser with a positive history of penicillin hypersensitivity and anaphylactic shock during previous general anesthesia, whose in vivo and in vitro allergy tests were positive for neuromuscular blocking agents, opioids, and midazolam. Immediate-type hypersensitivity reactions to antibiotics and professional exposure to hairdressing products might induce simultaneous cross-sensitization to multiple drugs that are commonly used during general anesthesia.

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