• D Peña Otero, D Vazquez Domínguez, and L Hernanz Fernández.
• Professor, University General Hospital Gregorio Marañón; Gregorio Marañón Healthcare Research Institute-Nursing Department (IiSGM); Centre for Health Sciences San Rafael-Antonio Nebrija University, Madrid, Spain.
• J Wound Care. 2017 Mar 2; 26 (3): 128-136.

ObjectiveTo comparatively assess the efficacy of four different therapeutic strategies to prevent the development of facial pressure ulcers (FPUs) related to the use of non-invasive mechanical ventilation (NIV) with oro-nasal masks in critically ill hospitalised patients.MethodThis randomised control trial was performed at the high dependency unit in the University General Hospital Gregorio Marañón in Madrid, Spain. Overall, 152 patients with acute respiratory failure were recruited. All patients were hospitalised and received NIV through oro-nasal masks. The Norton tool was used to evaluate the general risk of developing pressure ulcers (PUs). Subjects were divided into four groups, each of them receiving a different treatment. Tissue assessment and preventive care were performed by a member of the research team.ResultsThe incidence of FPUs was significantly lower in the group receiving a solution of hyperoxygenated fatty acids (HOFA) when compared with each of the other therapeutic strategies: direct mask (p=0.055), adhesive thin dressing (p=0.03) and adhesive foam dressing (p<0.001).ConclusionThe application of HOFA on the facial skin in contact with the oro-nasal masks showed the highest efficacy in the prevention of NIV-related FPUs.

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