• A Tidholm, A Bodegård-Westling, K Höglund, J Häggström, and I Ljungvall.
• Anicura Albano Animal Hospital, Danderyd, Sweden.
• J. Vet. Intern. Med. 2017 Mar 1; 31 (2): 303-310.

BackgroundEffective regurgitant orifice area (EROA), calculated from the vena contracta width (VCW) as the narrowest portion of the proximal regurgitant jet, might be used to estimate severity of mitral regurgitation. However, this simplified assumption only holds when the EROA is circular, which might not be true in dogs with myxomatous mitral valve disease (MMVD).HypothesisEffective regurgitant orifice area in dogs with MMVD is noncircular, and using color Doppler real-time 3-dimensional (RT3D) echocardiography, measured EROA in the en face view will be significantly different from calculated EROA.AnimalsHundred and fifty-eight privately owned dogs with naturally occurring MMVD.Materials And MethodsProspective observational study comparing en face view of EROA with calculated EROA using VCW in 4-chamber (4Ch) and 2-chamber (2Ch) view only or combined 4Ch and 2Ch views using RT3D echocardiography.ResultsThe calculated EROA using the 2Ch view showed a systematic underestimation of 17% compared with the measured en face EROA corrected for body surface area. The calculated EROA using 4Ch and 4Ch + 2Ch views showed less agreement with the en face EROA, and the difference between methods increased with increasing EROA. The difference between calculated and measured EROA showed a systematic underestimation of the calculated EROA by 36% (4Ch) and 33% (4Ch + 2Ch), respectively, compared to measured en face EROA.Conclusion And Clinical ImportanceWhen replacing measured EROA with calculated EROA using VCW measurements, the 2Ch view is preferred in dogs with MMVD.Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

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