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- Tatsuya Tokura, Takuhei Murase, Takayuki Toriyama, Yuji Totani, Masataka Negita, Kaoru Akaza, Hiroaki Ozawa, Atsuko Nakagawa, and Shigeo Nakamura.
- Department of Internal Medicine, Nishio Municipal Hospital, 6 Kamiawara, Kumami-cho, Nishio 445-8510.
AbstractA 57-year-old man was admitted with fever and epigastralgia, and presented with splenomegaly and pancytopenia. A CT scan revealed splenic infarctions. There were no lymphadenopathies, skin lesions, or neurological abnormalities. A splenectomy was performed. Bone marrow involvement with hemophagocytosis was noted. The diagnosis of Asian variant of intravascular diffuse large B-cell lymphoma was based on intravascular and sinusoidal distribution of large CD5+ B cells. The patient died of the disease 11 months after onset. To our knowledge, this is the first report of AIVL that presented with splenic infarction. This distinct lymphoma should be included in the differential diagnosis of splenic infarction.
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