• Cornelia S Seitz, Eva-B Bröcker, and Axel Trautmann.
• Department of Dermatology, Venerology and Allergology, University of Würzburg, Josef Schneider Strasse 2, D-97080 Würzburg, Germany.
• Emerg Med J. 2007 Mar 1; 24 (3): e19.

AbstractAnaphylaxis is traditionally diagnosed and treated as an acute emergency but should be always followed by a search for specific triggers, resulting in avoidance strategies. This case report highlights the relevance of a detailed evaluation after anaphylaxis for diagnosis of a rare but potentially life-threatening allergy. Considering the high frequency of clobutinol application, IgE-mediated allergic hypersensitivity seems extremely rare and has to be distinguished from infection-associated urticaria and angioedema as well as non-specific summation effects. Accidental re-exposure has to be strictly avoided and therefore after identification of clobutinol as the anaphylaxis trigger, the patient received detailed allergy documents including international non-proprietary and trade names of the culprit drug.

17 keywords...

hide…