• Scientific reports · Jul 2015

    Localization-based full-field microscopy: how to attain super-resolved images.

    • Taehwang Son, Wonju Lee, and Donghyun Kim.
    • School of Electrical and Electronic Engineering Yonsei University, Seoul, 120-749 Korea.
    • Sci Rep. 2015 Jul 23; 5: 12365.

    AbstractIn this study, we have investigated localization-based microscopy to achieve full-field super-resolution. For localized sampling, we have considered combs consisting of unit pulses and near-fields localized by surface nanoapertures. Achievable images after reconstruction were assessed in terms of peak signal-to-noise ratio (PSNR). It was found that spatial switching of individual pulses may be needed to break the diffraction limit. Among the parameters, the resolution was largely determined by sampling period while the effect of width of a sampling pulse on PSNR was relatively limited. For the range of sampling parameters that we considered, the highest resolution achievable is estimated to be 70 nm, which can further be enhanced by optimizing the localization parameters.

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