• Cleve Clin J Med · Jun 2008

    Review

    Meta-analysis: Its strengths and limitations.

    • Esteban Walker, Adrian V Hernandez, and Michael W Kattan.
    • Department of Quantitative Health Sciences, Cleveland Clinic Foundation, OH 44195, USA. walkere1@ccf.org
    • Cleve Clin J Med. 2008 Jun 1; 75 (6): 431-9.

    AbstractNowadays, doctors face an overwhelming amount of information, even in narrow areas of interest. In response, reviews designed to summarize the large volumes of information are frequently published. When a review is done systematically, following certain criteria, and the results are pooled and analyzed quantitatively, it is called a meta-analysis. A well-designed meta-analysis can provide valuable information for researchers, policymakers, and clinicians. However, there are many critical caveats in performing and interpreting them, and thus many ways in which meta-analyses can yield misleading information.

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