• Critical care clinics · Apr 2019

    Review

    New Agents for the Treatment of Type 2 Diabetes.

    • Renata Libianto and Elif I Ekinci.
    • Department of Medicine, The University of Melbourne, Austin Health, 300 Waterdale Road, Heidelberg West, Melbourne, Victoria 3081, Australia.
    • Crit Care Clin. 2019 Apr 1; 35 (2): 315-328.

    AbstractThe Renaissance of glucose-lowering therapies has arrived with multiple agents that lower blood glucose and demonstrate cardiovascular and renal benefits in people with type 2 diabetes. This article summarizes these new classes of therapies, including the sodium glucose co-transporter-2 inhibitors, glucagon-like peptide-1 agonists, and dipeptidyl peptidase-4 inhibitors. Their cardiovascular safety profile, effects on glycemic, weight, and renal outcomes are discussed. As more options become available to treat type 2 diabetes, clinicians need to be aware of the advantages of each class of medications, beyond their glycemic lowering effects. The safety profiles are summarized in this article.Copyright © 2018 Elsevier Inc. All rights reserved.

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