• J. Clin. Pathol. · Mar 2011

    Review

    Practical management of antibiotic allergy in adults.

    • Andrew McLean-Tooke, Catherine Aldridge, Catherine Stroud, and Gavin P Spickett.
    • Department of Immunology, Fremantle Hospital and PathWest Laboratory Medicine, Fremantle, Perth, Australia. andymctooke@yahoo.co.uk
    • J. Clin. Pathol. 2011 Mar 1; 64 (3): 192-9.

    AbstractThis review looks at the main issues around immediate hypersensitivity and the role and limitations of testing. The majority of literature on antibiotic hypersensitivity relates to β-lactam antibiotics, mainly because of the heavy usage of this class of drugs. Concerns around cross-reactivity always worry clinicians, particularly in the emergency situation. Reasonable data now exist in relation to β-lactam antibiotics and derivatives, which enable appropriate risk management to be undertaken. The available literature for other classes of antibiotics is also discussed.

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